I practice a lot. The inside of my right thumb has a tendency to get blisters. My first line of defence is to put a bandaid around my thumb with the pad of the bandaid on top of the sore area. Then I wrap a piece of medical tape around that to make sure it stays on.
If I’m past the point of no return on blisters all over my hands I resort to a golf glove. I use fingerless ones in warm weather and regular ones in cold weather.